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TGF-ß Family
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Description:
Transforming Growth Factor-ß3 (TGF-ß3) is one of a family of transforming growth factors identified in mammals. TGFßs mediate their activity by high affinity binding to the TGFß type II receptor which signals through a serine/threonine kinase pathway.
References:
Pellaud, J, Schote, U, Arvinte, T and Seelig, J (1999) J. Biol. Chem. 274, 7699-7704
Source:
Produced recombinantly in E. coli
Purity:
>95% pure (by HPLC)
Molecular Weight:
25,427 daltons
N-terminal sequence analysis:
5 residues - >95% single sequence
Biological Activity:
IC50 0.75 ng/ml
State and Appearance:
Lyophilized white powder. Contains mannitol.
Storage/Stability:
The lyophilized powder is stable at -20°C or -80°C.
Reconstitution:
Reconstitute in acetic acid, pH <3.8 in 20 % ethanol at a concentration of > 50 µg/ml.
Reconstitution:
#1800: Handling of TGF-ß3
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